Investigation of interaction between different types of laser lights with biological tissues phantoms with nanoparticles

The purpose of this research is designing optical phantoms with optical properties mimicking human tissue,

and also assessing their similarity to the target tissues. The material used for manufacturing phantoms

was a substrates made of respectively PCV and PDMS, mixed with ink and carbon nanoparticles in various

proportions.

The optical properties measured in this study were absorption and scattering coefficients. These

parameters were examined by measuring the impulse response that is an output made by laser lights hitting

planer layers (phantoms) with various thicknesses. Moreover, for these measurements were used two laser

beams with wavelengths of 532nm and 1054nm. Additionally, this setup included thermal imaging camera

that helped with registration of impulse response on phantoms.

Results of performed studies show dependence between behavior of laser lights and penetration to the

same tissue phantoms on varying depths of penetration. Lastly, these results were compared to simulated

impulse responses of the materials obtained by the means of Monte Carlo computer simulations.

Measurements’ results of investigation in the subject were found to be in agreement with said simulations,

proving that the manufactured phantoms can be used as a substitute of human tissue in researches that

can vary in purpose.

Author: Dorota Truchanowicz
Conference: Title